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Increases In Leptin May Promote Colorectal Cancer



While researchers have known that obesity increases the risk for the development of colon cancer, the underlying molecular mechanisms have remained unclear.

Now, for the first time, a collaborative study of researchers at the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University's College of Science and Technology and the Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy have found that an increase in leptin, a cytokine that is normally increased in obese or overweight individuals, may promote colorectal neoplasms by activating colorectal cancer stem cells.Their findings appear in the journal, Endrocrine-Related Cancer.


For more details View the full story here

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